Understanding the genetic and epigenetic basis of cell identity and plasticity in regeneration and tumorigenesis
Check out our contributions to the latest COVID-19 research!
We investigated SARS-CoV-2 potential tropism by surveying expression of viral entry-associated genes in single-cell RNA-sequencing data from multiple tissues from healthy human donors…Read more
Here, we leverage human and non-human primate (NHP) single-cell RNA-sequencing (scRNA-seq) datasets to uncover the cell subsets that may serve as cellular targets of SARS-CoV-2…Read more
New paper in Cell
We utilized a reverse genetics system to generate a GFP reporter virus to explore SARS-CoV-2 pathogenesis and a luciferase reporter virus to demonstrate sera collected from SARS and COVID-19 patients…Read more
Brigid Hogan and Purushothama Rao Tata illustrate the cellular architecture of the respiratory system and highlight key cell types residing in different regions, including their markers, functions, lineage relationships and pathological relevance, as well as approaches to culturing and studying them in vitro.
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