Tata Lab Publications

Chromatin Remodeling of Colorectal Cancer Liver Metastasis is Mediated by an HGF-PU.1-DPP4 Axis

Lihua Wang, Ergang Wang, Jorge Prado Balcazar, Zhenzhen Wu, Kun Xiang, Yi Wang, Qiang Huang, Marcos Negrete, Kai-Yuan Chen, Wei Li, Yujie Fu, Anders Dohlman, Robert Mines, Liwen Zhang, Yoshihiko Kobayashi, Tianyi Chen, Guizhi Shi, John Paul Shen, Scott Kopetz, Purushothama Rao Tata, Victor Moreno, Charles Gersbach, Gregory Crawford, David Hsu, Emina Huang, Pengcheng Bu, Xiling Shen.  Published in Adv Sci. Aug 2021


COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets

Toni M. Delorey, Carly G. K. Ziegler, Graham Heimberg, … Purushothama Rao Tata, et al.   Published in Nature. Apr 2021


Ferroptotic stress promotes the accumulation of pro-inflammatory proximal tubular cells in maladaptive renal repair

Ide S, Kobayashi Y, Ide K, Strausser SA, Abe K, Herbek S, O’Brien LL, Crowley SD, Barisoni L, Tata A, Tata PR, Souma T.  Published in Elife. Jul 2021


Epithelial cell plasticity: breaking boundaries and changing landscapes

Tata A, Chow RD, Tata PR.  Published in EMBO Reports. Jul 2021


Secretory Cells Dominate Airway CFTR Expression and Function in Human Airway Superficial Epithelia

Okuda K, Dang H, Kobayashi Y, Carraro G, Nakano S, Chen G, Kato T, Asakura T, Gilmore RC, Morton LC, Lee RE, Mascenik T, Yin WN, Barbosa Cardenas SM, O’Neal YK, Minnick CE, Chua M, Quinney NL, Gentzsch M, Anderson CW, Ghio A, Matsui H, Nagase T, Ostrowski LE, Grubb BR, Olsen JC, Randell SH, Stripp BR, Tata PR, O’Neal WK, Boucher RC.  Published in Am J Respir Crit Care Med. May 2021


Identification of a Repair-Supportive Mesenchymal Cell Population during Airway Epithelial Regeneration

Moiseenko A, Vazquez-Armendariz AI, Kheirollahi V, Chu X, Tata A, Rivetti S, Günther S, Lebrigand K, Herold S, Braun T, Mari B, De Langhe S, Kwapiszewska G, Günther A, Chen C, Seeger W, Tata PR, Zhang JS, Bellusci S, El Agha E.  Published in Cell Reports. Dec 2020


Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction

Katsura H, Sontake V, Tata A, Kobayashi Y, Edwards CE, Heaton BE, Konkimalla A, Asakura T, Mikami Y, Fritch EJ, Lee PJ, Heaton NS, Boucher RC, Randell SH, Baric RS, Tata PR. Published in Cell Stem Cell. Dec 2020


BALO: a “mini lung” model to study cell-cell interactions

Sontake V, Tata PR.  Published in EMBO J. Nov 2020


Persistence of a regeneration-associated, transitional alveolar epithelial cell state in pulmonary fibrosis. 

Kobayashi Y, Tata A, Konkimalla A, Katsura H, Lee RF, Ou J, Banovich NE, Kropski JA, Tata PR.  Published in Nature Cell Biology. Aug 2020


Essential role for InSyn1 in dystroglycan complex integrity and cognitive behaviors in mice

Uezu A, Hisey E, Kobayashi Y, Gao Y, Bradshaw TW, Devlin P, Rodriguiz R, Tata PR, Soderling S.  Published in Elife. Dec 2019


Cellular organization and biology of the respiratory system

Hogan B, Tata PR. Published in Nature Cell Biol. Jul 2019


IL-1 and TNFα Contribute to the Inflammatory Niche to Enhance Alveolar Regeneration

Katsura H, Kobayashi Y, Tata PR, Hogan BLM. Published in Stem Cell Reports. Apr 2019


ABL kinase inhibition promotes lung regeneration through expansion of an SCGB1A1+ SPC+ cell population following bacterial pneumonia

Khatri A, Kraft BD, Tata PR, Randell SH, Piantadosi CA, Pendergast AM. Published in PNAS. Apr 2019


A revised airway epithelial hierarchy includes CFTR-expressing ionocytes.

Montoro DT, Haber AL, Biton M, Vinarsky V, Lin B, Birket SE, Yuan F, Chen S, Leung HM, Villoria J, Rogel N, Burgin G, Tsankov AM, Waghray A, Slyper M, Waldman J, Nguyen L, Dionne D, Rozenblatt-Rosen O, Tata PR, Mou H, Shivaraju M, Bihler H, Mense M, Tearney GJ, Rowe SM, Engelhardt JF, Regev A, Rajagopal J. Published in Nature. Aug 2018


Pulmonary Neuroendocrine Cells: Sensors and Sentinels of the Lung

Kobayashi Y, Tata PR.  Published in Developmental Cell. May 2018


Myoepithelial Cells of Submucosal Glands Can Function as Reserve Stem Cells to Regenerate Airways after Injury

Tata A, Kobayashi Y, Chow RD, Tran J, Desai A, Massri AJ, McCord TJ, Gunn MD, Tata PR.  Published in Cell Stem Cell. May 2018


Developmental History Provides a Roadmap for the Emergence of Tumor Plasticity

Tata PR, Chow RD, Saladi SV, Tata A, Konkimalla A, Bara A, Montoro D, Hariri LP, Shih AR, Mino-Kenudson M, Mou H, Kimura S, Ellisen LW, Rajagopal J. Published in Developmental Cell. Mar 2018


Plasticity in Olfactory Epithelium: Is It a Sniffer or Shape Shifter? 

Konkimalla A, Tata PR. Published in Cell Stem Cell. Dec 2017


Plasticity in the lung: making and breaking cell identity

Tata PR, Rajagopal J. Published in Developmental Cell. Mar 2017


The CapZ interacting protein Rcsd1 is required for cardiogenesis downstream of Wnt11a in Xenopus laevis

Hempel A, Kühl SJ, Rothe M, Rao Tata P, Sirbu IO, Vainio SJ, Kühl M. Published in Developmental Biology. Feb 2017


Regulatory Circuits and Bi-directional Signaling between Stem Cells and Their Progeny

Tata PR, Rajagopal J. Published in Cell Stem Cell. Dec 2016


Cellular plasticity: 1712 to the present day

Tata PR, Rajagopal J. Published in Curr Opin Cell Biol. Dec 2016


Dual SMAD Signaling Inhibition Enables Long-Term Expansion of Diverse Epithelial Basal Cells

Mou H, Vinarsky V, Tata PR, Brazauskas K, Choi SH, Crooke AK, Zhang B, Solomon GM, Turner B, Bihler H, Harrington J, Lapey A, Channick C, Keyes C, Freund A, Artandi S, Mense M, Rowe S, Engelhardt JF, Hsu YC, Rajagopal J. Published in Cell Stem Cell. Aug 2016


Parent stem cells can serve as niches for their daughter cells

Pardo-Saganta A, Tata PR, Law BM, Saez B, Chow RD, Prabhu M, Gridley T, Rajagopal J. Published in Nature. Jul 2015


Injury induces direct lineage segregation of functionally distinct airway basal stem/progenitor cell subpopulations

Pardo-Saganta A, Law BM, Tata PR, Villoria J, Saez B, Mou H, Zhao R, Rajagopal J. Published in Cell Stem Cell. Feb 2015