Tata Lab Publications

Ferroptotic stress promotes the accumulation of pro-inflammatory proximal tubular cells in maladaptive renal repair

Ide S, Kobayashi Y, Ide K, Strausser SA, Abe K, Herbek S, O’Brien LL, Crowley SD, Barisoni L, Tata A, Tata PR, Souma T.  Published in Elife. Jul 2021

Epithelial cell plasticity: breaking boundaries and changing landscapes

Tata A, Chow RD, Tata PR.  Published in EMBO Reports. Jul 2021

Secretory Cells Dominate Airway CFTR Expression and Function in Human Airway Superficial Epithelia

Okuda K, Dang H, Kobayashi Y, Carraro G, Nakano S, Chen G, Kato T, Asakura T, Gilmore RC, Morton LC, Lee RE, Mascenik T, Yin WN, Barbosa Cardenas SM, O’Neal YK, Minnick CE, Chua M, Quinney NL, Gentzsch M, Anderson CW, Ghio A, Matsui H, Nagase T, Ostrowski LE, Grubb BR, Olsen JC, Randell SH, Stripp BR, Tata PR, O’Neal WK, Boucher RC.  Published in Am J Respir Crit Care Med. May 2021

Identification of a Repair-Supportive Mesenchymal Cell Population during Airway Epithelial Regeneration

Moiseenko A, Vazquez-Armendariz AI, Kheirollahi V, Chu X, Tata A, Rivetti S, Günther S, Lebrigand K, Herold S, Braun T, Mari B, De Langhe S, Kwapiszewska G, Günther A, Chen C, Seeger W, Tata PR, Zhang JS, Bellusci S, El Agha E.  Published in Cell Reports. Dec 2020

Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction

Katsura H, Sontake V, Tata A, Kobayashi Y, Edwards CE, Heaton BE, Konkimalla A, Asakura T, Mikami Y, Fritch EJ, Lee PJ, Heaton NS, Boucher RC, Randell SH, Baric RS, Tata PR. Published in Cell Stem Cell. Dec 2020

BALO: a “mini lung” model to study cell-cell interactions

Sontake V, Tata PR.  Published in EMBO J. Nov 2020

Persistence of a regeneration-associated, transitional alveolar epithelial cell state in pulmonary fibrosis. 

Kobayashi Y, Tata A, Konkimalla A, Katsura H, Lee RF, Ou J, Banovich NE, Kropski JA, Tata PR.  Published in Nature Cell Biology. Aug 2020

Essential role for InSyn1 in dystroglycan complex integrity and cognitive behaviors in mice

Uezu A, Hisey E, Kobayashi Y, Gao Y, Bradshaw TW, Devlin P, Rodriguiz R, Tata PR, Soderling S.  Published in Elife. Dec 2019

Cellular organization and biology of the respiratory system

Hogan B, Tata PR. Published in Nature Cell Biol. Jul 2019

IL-1 and TNFα Contribute to the Inflammatory Niche to Enhance Alveolar Regeneration

Katsura H, Kobayashi Y, Tata PR, Hogan BLM. Published in Stem Cell Reports. Apr 2019

ABL kinase inhibition promotes lung regeneration through expansion of an SCGB1A1+ SPC+ cell population following bacterial pneumonia

Khatri A, Kraft BD, Tata PR, Randell SH, Piantadosi CA, Pendergast AM. Published in PNAS. Apr 2019

A revised airway epithelial hierarchy includes CFTR-expressing ionocytes.

Montoro DT, Haber AL, Biton M, Vinarsky V, Lin B, Birket SE, Yuan F, Chen S, Leung HM, Villoria J, Rogel N, Burgin G, Tsankov AM, Waghray A, Slyper M, Waldman J, Nguyen L, Dionne D, Rozenblatt-Rosen O, Tata PR, Mou H, Shivaraju M, Bihler H, Mense M, Tearney GJ, Rowe SM, Engelhardt JF, Regev A, Rajagopal J. Published in Nature. Aug 2018

Pulmonary Neuroendocrine Cells: Sensors and Sentinels of the Lung

Kobayashi Y, Tata PR.  Published in Developmental Cell. May 2018

Myoepithelial Cells of Submucosal Glands Can Function as Reserve Stem Cells to Regenerate Airways after Injury

Tata A, Kobayashi Y, Chow RD, Tran J, Desai A, Massri AJ, McCord TJ, Gunn MD, Tata PR.  Published in Cell Stem Cell. May 2018

Developmental History Provides a Roadmap for the Emergence of Tumor Plasticity

Tata PR, Chow RD, Saladi SV, Tata A, Konkimalla A, Bara A, Montoro D, Hariri LP, Shih AR, Mino-Kenudson M, Mou H, Kimura S, Ellisen LW, Rajagopal J. Published in Developmental Cell. Mar 2018

Plasticity in Olfactory Epithelium: Is It a Sniffer or Shape Shifter? 

Konkimalla A, Tata PR. Published in Cell Stem Cell. Dec 2017

Plasticity in the lung: making and breaking cell identity

Tata PR, Rajagopal J. Published in Developmental Cell. Mar 2017

The CapZ interacting protein Rcsd1 is required for cardiogenesis downstream of Wnt11a in Xenopus laevis

Hempel A, Kühl SJ, Rothe M, Rao Tata P, Sirbu IO, Vainio SJ, Kühl M. Published in Developmental Biology. Feb 2017

Regulatory Circuits and Bi-directional Signaling between Stem Cells and Their Progeny

Tata PR, Rajagopal J. Published in Cell Stem Cell. Dec 2016

Cellular plasticity: 1712 to the present day

Tata PR, Rajagopal J. Published in Curr Opin Cell Biol. Dec 2016

Dual SMAD Signaling Inhibition Enables Long-Term Expansion of Diverse Epithelial Basal Cells

Mou H, Vinarsky V, Tata PR, Brazauskas K, Choi SH, Crooke AK, Zhang B, Solomon GM, Turner B, Bihler H, Harrington J, Lapey A, Channick C, Keyes C, Freund A, Artandi S, Mense M, Rowe S, Engelhardt JF, Hsu YC, Rajagopal J. Published in Cell Stem Cell. Aug 2016

Parent stem cells can serve as niches for their daughter cells

Pardo-Saganta A, Tata PR, Law BM, Saez B, Chow RD, Prabhu M, Gridley T, Rajagopal J. Published in Nature. Jul 2015

Injury induces direct lineage segregation of functionally distinct airway basal stem/progenitor cell subpopulations

Pardo-Saganta A, Law BM, Tata PR, Villoria J, Saez B, Mou H, Zhao R, Rajagopal J. Published in Cell Stem Cell. Feb 2015